Antidepressant use during pregnancy and the risk of autism spectrum disorder in children

The association between the use of antidepressants during gestation and the risk of autism spectrum disorder (ASD) in children is still controversial. The aetiology of ASD remains unclear, although studies have implicated genetic predispositions, environmental risk factors, and maternal depression.

This study found the use of antidepressants, specifically selective serotonin reuptake inhibitors, during the second and/or third trimester increases the risk of ASD in children, even after considering maternal depression.

T Bouhkris et al (2015) Antidepressant use during pregnancy and the risk of autism spectrum disorder in children JAMA

 

Depression common among men with autism

Most men with autism have psychiatric disorders such as depression, finds a study of 50 men diagnosed with the disorder roughly 20 years ago. The findings highlight the range of challenges for adults with autism, many of whom lack the help they need. SFARI

IC Gillberg et al Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis Journal of Autism and Developmental Disorders 2015