Antidepressant use during pregnancy and the risk of autism spectrum disorder in children

The association between the use of antidepressants during gestation and the risk of autism spectrum disorder (ASD) in children is still controversial. The aetiology of ASD remains unclear, although studies have implicated genetic predispositions, environmental risk factors, and maternal depression.

This study found the use of antidepressants, specifically selective serotonin reuptake inhibitors, during the second and/or third trimester increases the risk of ASD in children, even after considering maternal depression.

T Bouhkris et al (2015) Antidepressant use during pregnancy and the risk of autism spectrum disorder in children JAMA

 

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